Efficacy and safety of fluticasone furoate nasal spray in adult and adolescent subjects with uncomplicated acute rhinosinusitis
نویسندگان
چکیده
Methods This randomized, double-blind, placebo-controlled, parallel-group, multicenter, 2-week treatment study evaluated FFNS 110 mcg once daily, twice daily vs. placebo in adults/ adolescents with uncomplicated ARS. Eligibility criteria reflected a clinical diagnosis and eliminated confounding conditions like common cold, symptomatic allergic rhinitis (AR), and other sinonasal conditions. Subjects with daily major symptom score (MSS; a composite score of 3 symptoms [nasal congestion/stuffiness, sinus headache/pressure or facial pain/pressure, and postnasal drip on a 0-3 scale]) >4.5 at baseline were randomized.
منابع مشابه
Efficacy and safety of mometasone furoate nasal spray in allergic rhinitis, acute rhinosinusitis and nasal polyposis
Seasonal and perennial allergic rhinitis, acute rhinosinusitis and nasal polyposis are inflammatory conditions of the nose and/or sinuses that produce bothersome symptoms and markedly affect patients’ quality of life [1–3]. These diseases frequently coexist, suggesting that each may be a manifestation of an inflammatory process within the continuous airway [3–5]. Clinical treatment guidelines f...
متن کاملAn open label, active controlled, multicentric clinical trial to assess the efficacy and safety of fluticasone furoate nasal spray in adult Indian patients suffering from allergic rhinitis.
BACKGROUND Allergic rhinitis is a common upper respiratory tract inflammation associated with a significant morbidity in all the age groups. Fluticasone furoate is a new potent topical glucocorticoid for the treatment of allergic rhinitis. OBJECTIVE To compare efficacy and safety of fluticasone furoate (FF) nasal spray 110 microg/day with fluticasone propionate (FP) nasal spray 200 microg/day...
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Department of Otorhinolaryngology, Faculty of Medicine, University of Defense Military Medical Academy, Belgrade, Serbia General Hospital Medigroup, Belgrade, Serbia Department of Pharmacokinetics and Clinical Pharmacy, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia ENT Hospital, Dr. Zutic, Belgrade, Serbia Institute for Pharmacy, Faculty of Medicine, University of Defense Milita...
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عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2011